Excited to see star grad student Leah Ziolkowski present her work on the role of ATF4 in pancreatic cancer at #AACR25 where she has discovered a novel role for ATF4 in sensing cellular nutrient stress and Kras activation. This work has implications for early diagnosis...

Proud of Alexandra Ware, second year graduate student in the lab presenting our work on the role of BNIP3 in cancer cachexia #AACR25. Loss of BNIP3 protects against muscle wasting in a mouse model of PDAC and also limits rates of progression to malignant disease. We...

Lara (senior undergrad in the lab graduating in June 2025) presents her research on role of BNIP3 in mTORC1 signaling in the liver at UChicago Undergraduate Research Day (Friday) followed next day by presenting at the Undergrad symposium #AACR25.

Leah wins award at UCCCC Trainee Associate member symposium!

Dr. Macleod was awarded the Hospira Foundation Professorship in Oncology in a ceremony taking place December 9th 2024 at the University of Chicago Quad club and attended by family, lab members and faculty colleagues from across the Biological Sciences Division and the...

The Y-Me board visited with Dr. Macleod and members of her lab (Niamh and Kate) working to understand and target metastatic breast cancer with a focus on the role of NIX in promoting epithelial-mesenchymal transition (EMT), an early critical step in the metastatic...

Was wonderful to return to MIT to give a seminar on our research on mitophagy in cancer as part of the MIT Cancer Center's 50th anniversary celebrations and catch up with so many influential scientists, including my former postdoc mentor Prof. Tyler Jacks! Also Bob...

Celebrating 30 years of Y-Me raising money to support breast cancer research! Honored to meet up with the amazing Y-Me ladies including Ginger Rugai, Katie McAlinden and many others playing softball all day, celebrating survivors and remembering those who lost their...

Privileged to have the NCI director, Dr. Kimryn Rathmell come to visit to give an inspirational talk to young scientists including our T32 supported trainees.

Dr. Huiping Liu, the first PhD student from the Macleod Lab (2002-2007) was guest speaker in the UCCCC 50th anniversary seminar series! Now a Professor at Northwestern University in Chicago, Huiping researches how to target breast cancer stem cells. Proud of you...

The Pancreatic Cancer Working Group including Dr. Macleod at the University of Chicago Comprehensive Cancer Center convened the first PancMidwest Pancreatic Cancer Research Symposium in May 2024 (https://voices.uchicago.edu/pancmidwest/).  In total, 130 researchers...

Thea was awarded a F31 fellowship from NIDDK for her research proposal to examine the role of BNIP3 in lipid homeostasis in the liver while Leah was awarded her F31 by NCI to define novel functions of ATF4 in pancreatic cancer. Congrats to both of them! Well deserved...

  Postdoctoral Position Available in Liver Cancer Research We are looking for a postdoctoral researcher to work in our liver cancer team examining the role of BNIP3 and NIX in modulating mitophagy and metabolism in the liver and how disruption of these mechanisms...

  Saying goodbye and thanks for all your hard work to summer undergraduate researcher, Ben Sachs who heads back to his sophomore year in college. Became a western wizard, RNA extraction, qPCR and mouse log management all mastered! An extra pair of hands for Thea...

Second year Macleod Lab graduate student in the Molecular Metabolism & Nutrition program passes her qualifying exam with flying colors and is now officially entered into candidacy for her PhD. Well done Leah on a beautiful presentation, some really novel...

Our work showing a role for BNIP3 in suppressing hepatocellular carcinoma (HCC) via turnover of lipid with mitochondria is published in Science Advances. Featured on the journal's website and on Biomedical picture of the day (http://bpod.mrc.ac.uk/archive/2022/12/3)!...

Enjoying a lab summer evening dinner at Nellas in Hyde Park - the best pizza in Chicago and that is quite the claim!

The last Saturday in August each year, the amazing Ginger Rugai and her team of fearless women organize a softball tournament in Beverly/Evergreen Park/Mount Greenwood neighborhoods to raise money for breast cancer research. The over 50 teams compete in a knockout...